Milstein Catalyst Precursor

Milstein Catalyst Precursor - Names and Identifiers

Name	Carbonylchlorohydrido[6-(di-t-butylphosphinomethyl)-2-(N,N-diethylaminomethyl)pyridine]ruthenium(II), min. 98% (Milstein Catalyst Precursor)
Synonyms	Milstein Catalyst Precursor [2-(Di-tert-butylphosphinoMethyl)-6-(diethylaMinoMethyl)pyridine]carbonylchlorohydridorutheniuM(II) [2-(Di-tert-butylphosphinomethyl)-6-(diethylaminomethyl)pyridine]ruthenium(II) chlorocarbonyl hydride Carbonylchlorohydrido[6-(di-tert-butylphosphinomethyl)-2-(N,N-diethylaminomethyl)pyridine]ruthenium(II)
CAS	863971-62-4

Milstein Catalyst Precursor - Physico-chemical Properties

Molecular Formula	C20H35ClN2OPR
Molar Mass	487.001
Appearance	solid
Color	pale yellow
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C
Sensitive	air sensitive

Milstein Catalyst Precursor - Risk and Safety

Hazard Symbols	Xn - Harmful
Risk Codes	R19 - May form explosive peroxides R40 - Limited evidence of a carcinogenic effect
Safety Description	36/37 - Wear suitable protective clothing and gloves.
WGK Germany	3

Milstein Catalyst Precursor - Introduction

Carbonylchlorohydrido[6-(di-t-butylphosphinomethyl)-2-(N,N-diethylaminomethyl)pyridine]ruthenium(II), min. 98% (Milstein Catalyst Precursor) is a transition metal complex, usually used as a Catalyst in organic synthesis.

The main properties of the compound include:
-Molecular formula: C27H49ClN2PRu
-Molecular weight: 607.10g/mol
-Appearance: light yellow solid
-Melting Point: Not Applicable
-Boiling Point: Not Applicable
-Solubility: Soluble in organic solvents such as chloroform, ether and acetone

Carbonylchlorohydrido[6-(di-t-butylphosphinomethyl)-2-(N,N-diethylaminomethyl)pyridine]ruthenium(II), min. 98% (Milstein Catalyst Precursor) is mainly used as follows:
-as a transition metal catalyst in organic synthesis, participating in carbonylation reaction, hydrogenation reaction and hydrogen transfer reaction
-For the synthesis of synthetic drugs, natural products and organic molecules
-Play an important role in the conversion of carbonyl alkenes and alkynes

The preparation method of the complex mainly includes two steps:
1. First, thallium chloride and 2-(dimethylaminomethyl)-6-(di-tert-butylphosphinomethyl) pyridine are reacted to give [6-(di-tert-butylphosphinomethyl)-2-(dimethylaminomethyl) pyridine] Thallium chloride.
2. Then, by reacting with a ruthenium compound (such as [RuCl2(PPh3)3]), under appropriate reaction conditions, the thallium chloride is replaced with the carbonyl of the ruthenium compound, this gives Carbonylchlorohydrido[6-(di-t-butylphosphinomethyl)-2-(N,N-diethylaminomethyl)pyridine]ruthenium(II), min. 98% (Milstein Catalyst Precursor).

For safety information, the following handling and storage precautions are recommended:
-Wear appropriate personal protective equipment, including chemical protective gloves and goggles.
-Avoid contact with skin, eyes and respiratory system to prevent inhalation or ingestion.
-Operate in a well-ventilated area to avoid dust, smoke or vapor.
-Store in a dry, cool place, away from fire and flammable materials.
-Do not contact with oxidants and strong acids to avoid dangerous reactions.

The above information is for reference only. Please refer to relevant literature and official safety data sheets for specific operation and use.

Last Update：2024-04-09 21:01:54